Application of Neurochemical Markers for Assessing Health Effects after Developmental Methylmercury and PCB Coexposure

Table 1

Total Hg levels in blood and brain of rats perinatally treated with 1 mg MeHg/kg bw/day (GD7-PD7) and/or 20 mg PCB153/kg bw/day (GD10–GD16), alone and in combination.

	Blood Hg (μg/ml)			Brain Hg (μg/g)
	Dams	Offspring		Dams	Offspring
		Male	Female		Male	Female
Control	0.017±0.004; 𝑛=3	0.003±0.001; 𝑛=4	0.005±0.004; 𝑛=4	0.013	0.002	0.003
MeHg	11.33±2.26; 𝑛=4	1.35±0.40; 𝑛=4	1.31±0.40; 𝑛=4	7.53	1.67±0.43; 𝑛=4	1.52±0.33; 𝑛=4
MeHg + PCB153	10.74±1.95; 𝑛=5	1.33±0.33; 𝑛=5	1.26±0.20; 𝑛=5	8.78	2.80±1.81; 𝑛=6	1.63±0.20; 𝑛=6
PCB153	0.012±0.001; 𝑛=5	0.003±0.001; 𝑛=4	0.002±0.001; 𝑛=5	0.026	0.024±0.039; 𝑛=4	0.014±0.024; 𝑛=6

Data are the mean ± S.D.