Phospholipogenic Pharmaceuticals Are Associated with a Higher Incidence of Histological Findings than Nonphospholipogenic Pharmaceuticals in Preclinical Toxicology Studies

Figure 4

Percent phospholipogenics giving histological findings consistent with phospholipidosis, by organ. In response to phospholipogenic administration, lung and lymph node presented with the greatest number of histological findings that matched phospholipidosis descriptors whereas bone marrow and thymus presented with the least. The data represent that pooled from three species and all study durations.