Research Article

Modeling the Human Kinetic Adjustment Factor for Inhaled Volatile Organic Chemicals: Whole Population Approach versus Distinct Subpopulation Approach

Figure 5

Distributions of individual values obtained for several physiological parameters in each subpopulation within the whole virtual Canadian population. From top to bottom, distributions for body weight-adjusted alveolar ventilation rate (a), body weight-adjusted liver blood flow (b) and maximal rate of metabolism of benzene (c) and 1,4-dioxane (d) are shown for the entire Canadian population ( thick ), adults (—), children and adolescents (— –), elderly (–·–·–), toddlers (– – -), pregnant women (-------), infants (-·-·-·-), and neonates (indistinguishable).
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(a)
404329.fig.005b
(b)
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(c)
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(d)