Table 1: Chemical-specific parameters used in the steady-state algorithm.

ParameterChemical
Benzene(a)1,4-Dioxane(b)

Vmaxc (mg/h-kg0.75)2.110.27
Km (mg/L)0.13.0
Blood : air partition coefficient (Pb)7.43650
Exposure concentration (mg/m3, UF × RfC)(c)0.33

( a ) [22]. ( b ) [23]. ( c ) [10].
BW: body weight; Km: Michaëlis-Menten constant, Pb: blood : air partition coefficient, RfC: reference concentration; UF: interindividual uncertainty factor; Vmaxc: constant maximum rate of metabolism.