Research Article

Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation

Figure 6

Lowry plot of the eFAST quantitative measure. The total effect of a parameter 𝑆 𝑇 𝑖 comprised the main effect 𝑆 𝑖 (black bar) and any interactions with other parameters (grey bar) given as a proportion of variance. The ribbon, representing variance due to parameter interactions, is bounded by the cumulative sum of main effects (lower bold line) and the minimum of the cumulative sum of the total effects (upper bold line), (a) CV at 3 hours, (b) CXPPM at 3 hours, (c) Curine at 5 hours.
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(a) CV, 3 hours
760281.fig.006b
(b) CXPPM, 3 hours
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(c) Curine, 5 hours