Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation

Table 4

Model parameters accounting for 100% variance at different time points.

CV		CXPPM		Curine
3 h	5 h	3 h	5 h	5 h	8 h
QPC ^a	QPC	Pba	Pba	Rurine	Rurine
Pba	QspdC	QPC	QPC	CRE	BW
KM	KM	QCC	QspdC	BW	QPC
QCC	QCC	KM	KM	Pba	CRE
QliC	Pba	QliC	QCC	KM	VfaC
MPY	QliC	MPY	Prpda	QCC	Qspdc
Pspda	Prpda	Pspda	QliC	MPY	Pspda
BW	MPY	VliC	MPY	QliC	Pba
VliC	Pspda	BW	Pspda	QPC	QCC
		QspdC	VliC		Pfaa

^aItalicised abbreviations correspond to parameters measured for each volunteer listed in Table 1.