Research Article

Bayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats

Table 5

Population posterior distributions.

Parameter*μ (CV/R)Σ (CV/R)

v 01180.038 (0.02/1.0)0.24 (0.13/1.2)
v 01380.026 (0.02/1.2)0.35 (0.17/1.1)
v 01530.025 (0.02/1.3)0.35 (0.16/1.5)
v 01700.029 (0.02/1.0)0.38 (0.16/1.0)
v 01800.035 (0.02/1.1)0.31 (0.15/1.0)
v 01870.017 (0.02/1.1)0.55 (0.25/1.0)
𝑣 a l l 0 0.027 (0.03/1.0)0.43 (0.08/1.1)

𝐹 2 B 0.0025 (0.01/1.0)
𝐹 1 A 0.045 (0.02/1.2)

𝜎 f a t 0.30 (0.06/1.0)
0.23 (0.04/1.0)
𝜎 p l a s m a 0.19 (0.04/1.2)
0.23 (0.03/1.3)
𝜎 l i v e r 0.40 (0.05/1.1)
0.36 (0.03/1.0)

*Units for 𝑣 0 are (mL/h/kg0.75); 𝐹 is unitless.
CV: coefficient of variance of chain, R: Gelman-Rubin.
One value each for step 1 (top) and step 2 (bottom).