Research Article
In Silico Risk Assessment of HLA-A*02:06-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Caused by Cold Medicine Ingredients
Table 1
Ingredients contained in popular cold medicines available in Japan. Chinese herbs, vitamins, and lysozyme are excluded from the table.
| Drug name | Therapeutic category |
| Acetaminophen | Analgesic; antipyretic | Ambroxol | Expectorant | Bromhexine | Expectorant; mucolytic | Caffeine | CNS stimulant; respiratory stimulant | Carbinoxamine | Antihistaminic | d-Chlorpheniramine | Antihistaminic | Clemastine | Antihistaminic | Dextromethorphan | Antitussive | Dihydrocodeine | Analgesic (narcotic); antitussive | Ethenzamide | Analgesic | Guaiacol | Expectorant | Guaifenesin | Expectorant | Ibuprofen | Anti-inflammatory; analgesic; antipyretic | Isopropamide | Antispasmodic | Loxoprofen (R, S) | Anti-inflammatory; analgesic | Mequitazine | Antihistaminic | d-Methylephedrine | Analeptic | Noscapine | Antitussive | Pseudoephedrine | Decongestant | Tranexamic acid | Hemostatic |
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