The Effects of Eucheuma cottonii on Signaling Pathway Inducing Mucin Synthesis in Rat Lungs Chronically Exposed to Particulate Matter 10 (PM10) Coal Dust
Figure 2
The morphology of lung in rats exposed to chronic coal dust and the effects of E. Cottonii supplementation (Hematoxyline Eosin staining, Magnification ×20). CD6.25 induced lung parenchym edematous. This edematous process decreased in CD12.5 and became necrosis in CD25. Chronic coal dust exposure increased the diameter of alveolus lumen. Besides, massive inflammatory cells were found in all coal dust exposure groups. CD25 induces vasodilation and hemorrhagic. The oral administration of EC150 and EC300 is able to decreased the diameter of alveolus lumen similar to control, but inflammatory cells were still exist. In addition, this supplementation also is able to minimizes the hemorrhagic process.
