Assessment of Safety and Therapeutic Efficacy of Rosa damascena L. and Quercus infectoria on Cardiovascular Performance of Normal and Hyperlipidemic Rabbits: Physiologically Based Approach

Table 2

Pulse pressure and cardiac indices in different animal groups.

Groups	Pulse pressure (mmHg)	Max dp/dt (mmHg/s)	Min dp/dt (mmHg/s)	HR (beat/min)	PRP
CTL	33±5	4586±292	−2698±71	291±13	28±2
RD	28±4	4554±306	−2746±234	247±7	22.4±1.2
QI	32±3	4540±667	−3648±665	277±16	27.3±2.4
H	32±2	4877±324	−2734±217	274±11	26.5±1.4
H+RD	42±2	5689±946	−3618±254	276±8	31.6±2.1^∗
H+QI	42±2	5534±532	−3765±406	302±19	30.4±2.9

Values are Mean ± SEM. *𝑃<0.05 compared with RD. CTL: control; RD: Rosa damascena L.; QI: Quercus infectoria; H: Hyperlipidemic; H+RD: Hyperlipidemic+RD; H+QI: Hyperlipidemic+QI; PRP: Pressure-rate product ((MAP * heart rate) * 1,000⁻¹); max dp/dt: maximum velocity of contraction; min dp/dt: maximum velocity of relaxation.