Toxicologic Assessment of a Commercial Decolorized Whole Leaf Aloe Vera Juice, Lily of the Desert Filtered Whole Leaf Juice with Aloesorb
Table 4
Clinical chemistry of plasma from B6C3F1 mice administered aloe juice by gavage.
Parameters—3 days post exposure
Control male
Aloe male
Control female
Aloe female
ALT (U/L)
26.0 ± 3.5
23.0 ± 5.4
18.4 ± 2.0
19.7 ± 2.2
ALP (U/L)
64.2 ± 4.4
60.56 ± 7.3
87.8 ± 9.4
88.8 ± 16.4
CK (U/L)
287.6 ± 264.8
146.0 ± 114.7
85.4 ± 29.2
120.2 ± 68.3
TBIL (mg/dL)
≤0.1#
≤0.1
≤0.1
≤0.1
Total protein
4.5 ± 0.23
4.3 ± 0.1*
4.1 ± 0.13
4.0 ± 0.42
BUN (mg/dL)
18.0 ± 1.2
18.0 ± 1.4
22.8 ± 1.9
22.5 ± 1.1
Creatinine (mg/dL)
≤0.2#
≤0.2
≤0.2
≤0.2
Parameters—14 days post exposure
ALT (U/L)
25.2 ± 7.4
21.8 ± 6.5
23.2 ± 11.9
18.7 ± 2.4
ALP (U/L)
71.2 ± 18.0
67.4 ± 5.0
101.3 ± 3.9
86.2 ± 16.6
CK (U/L)
117.0 ± 14.3
169.2 ± 86.9
157.2 ± 105.5
196.0 ± 144.6
TBIL (mg/dL)
≤0.1#
≤0.1
≤0.1
≤0.1
Total protein
3.8 ± 0.06
4.0 ± 0.3
3.8 ± 0.03
3.8 ± 0.2
BUN (mg/dL)
20.8 ± 4.0
21.8 ± 2.6
24.3 ± 2.3
22.2 ± 1.0
Creatinine (mg/dL)
≤0.2#
≤0.2
≤0.2
≤0.2
Values expressed as mean ± s.d. . ALT: alanine aminotransferase activity; ALP: alkaline phosphatase Activity; CK: creatine kinase; TBIL: total bilirubin; BUN: blood urea nitrogen.
for TBIL and creatinine were at or below instrument quantitation threshold.
