Toxicologic Assessment of a Commercial Decolorized Whole Leaf Aloe Vera Juice, Lily of the Desert Filtered Whole Leaf Juice with Aloesorb

Table 8

Consumption of Aloe vera by rats in this study versus NTP drinking water study.

Doses of aloe	Target malic acid concentration	Malic acid molarity in dosed form (mM)	Consumption of dosed form (g/day)*	Weight of rats at 4 weeks (g)*	umol/day malic acid consumed/100 g body weight
NTP 1% in water	1980 (ppm)^∓	14.8	28.80 male; 22.46 female	200.0 male; 142.6 female	212.8 male; 232.8 female
Present study 100 g/kg	36.2 mmol/kg feed^∧	37.8^#	14.30 male; 9.13 female	239.0 male; 150.0 female	235.0 male; 229.3 female

^∓Taken from Table H4, Target values for malic acid administered to rats in the 2-year study at approximately 4 weeks, pg. 260 NTP study.
^∧Measured in Aloe feed extract.
*NTP data obtained from Tables J1 and J2, pgs. 283 and 284 NTP study.
^#Assumes 1 gram feed = 1 ml solid.