Scorpion Peptides: Potential Use for New Drug Development
Figure 1
Schematic proposed models for scorpion toxins use in cancer and metastasis therapy. Scorpion toxins are dotted with high specificity to targeted specific cells receptors enabling them to be potent candidate for drugs carrier. (a) Radioactive iodine delivery into brain gliomas using chlorotoxin as a guider to target cancerous cells. (b) The chlorotoxin triggers gene transfection for cancer cells therapy. (c) Direct effect of pertussis toxin in abolishing metastasis. It did inhibit migration (evasion) through blocking the transduction signal of the lysophosphatidic acid pathway.
