Antigenotoxic Effect of Curcumin and Carvacrol against Parathion Induced DNA Damage in Cultured Human Peripheral Blood Lymphocytes and Its Relation to GSTM1 and GSTT1 Polymorphism

Table 5

Effect of GSTT1 and GSTM1 polymorphism on antigenotoxicity of curcumin and carvacrol against parathion induced genotoxicity.

Genotype	Parathion (2.5 g/mL)	Parathion (2.5 g/mL) + curcumin (10 g/mL)	Parathion (2.5 g/mL) + carvacrol (2.5 g/mL)
Relationship with GSTT1
GSTT1 (nonnull)
GSTT1 (null)
Relationship with GSTM1
GSTM1 (nonnull)
GSTM1 (null)
Relationship with both GSTT1 and GSTM1
GSTT1 (nonnull), GSTM1 (nonnull)
GSTT1 (null), GSTM1 (null)
GSTT1 (nonnull), GSTM1 (null)
GSTT1 (null), GSTM1 (nonnull)

(nonsignificance as compared to GSTT1 nonnull genotypes).
(nonsignificance as compared to GSTM1 nonnull genotypes).
(nonsignificance as compared to GSTT1 and GSTM1 nonnull genotypes).
(nonsignificance as compared to GSTT1 nonnull and GSTM1 null genotypes).