Safety Evaluation of Artocarpus altilis as Pharmaceutical Agent in Wistar Rats

Table 2

Relative body (BW) and organ weights of control and experimental groups (g) (values in parenthesis indicate organ-BW ratio) (𝑛=6).

Group	Initial BW	Final BW	Liver	Kidney	Heart	Brain	Spleen
Con	161^a ± 9.67	152^a ± 7.63	4.29^a ± 0.53; (2.28)	1.05^a ± 0.27; (0.69)	0.45^a ± 0.15; (0.29)	1.42^a ± 0.95; (0.93)	0.32^a ± 0.01; (0.21)
ALA	183^a ± 5.83	168^a ± 2.01	5.19^a ± 0.31; (3.08)	1.29^a ± 1.38; (0.76)	0.62^a ± 0.23; (0.36)	1.56^a ± 0.80; (0.92)	0.35^a ± 0.01; (0.20)
ALM	161^a ± 4.31	150^a ± 8.43	4.46^a ± 0.75; (2.97)	1.16^a ± 0.25; (0.77)	0.60^a ± 0.42; (0.40)	1.57^a ± 0.77; (1.04)	0.34^a ± 0.01; (0.22)
ABA	172^a ± 6.66	155^a ± 5.28	4.11^a ± 0.77; (2.65)	1.16^a ± 0.37; (0.78)	0.61^a ± 0.64; (0.39)	1.50^a ± 0.97; (0.96)	0.28^a ± 0.03; (0.18)
ABM	172^a ± 5.52	184^b ± 5.96	5.52^a ± 0.87; (3.00)	1.42^a ± 0.31; (0.77)	0.62^a ± 0.28; (0.33)	1.47^a ± 1.02; (0.79)	0.36^a ± 0.02; (0.19)

ALA: leaf aqueous extract, ALM: leaf 80% MeOH, ABA: bark aqueous extract, ABM: bark 80% MeOH extract.
Mean values carrying different superscripts a, b, c … in columns differ significantly (𝑃≤0.05).