MeHg Developing Exposure Causes DNA Double-Strand Breaks and Elicits Cell Cycle Arrest in Spinal Cord Cells

Figure 1

Mercury deposition in the spinal cord of E10 control and MeHg-treated embryos examined by the AMG method. Spinal cord showing ependymal (e), mantle (mt), and marginal (mg) layers in low magnification (a) and high magnification (b). The brown color corresponds to the mercury deposits in cells (arrows) in MeHg-treated embryos. The accompanying table displays the intensity of mercury deposition in the cells of the spinal cord layers, classified as absent (−), mild (+), and moderate (++).

(a)

(b)