Neuroprotective Effects of Alpha-Mangostin on MPP⁺-Induced Apoptotic Cell Death in Neuroblastoma SH-SY5Y Cells

Figure 5

Effect of alpha-mangostin on nuclear morphology in MPP⁺-treated SH-SY5Y cells. Control cells were untreated (a). Treated cells were exposed to 10 μM of alpha-mangostin (b), 1000 μM MPP⁺ (c), or a combination of α-M and MPP⁺ (d) for 24 hours. Apoptotic nuclear morphology was visualized by DNA staining with Hoechst 33258. Percentage of cells with apoptotic nuclei was calculated (e). Data are expressed as mean ± SEM () of percentage to untreated cells. .

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