Chronic Exposure to Arsenic in Drinking Water Causes Alterations in Locomotor Activity and Decreases Striatal mRNA for the D2 Dopamine Receptor in CD1 Male Mice
Table 2
On- and off-wall rearing behavior.
Time of exposure
Control
0.5 mg As/L
5.0 mg As/L
On-wall rearing
Month 1
2.50 (6.00)
3.50 (8.00)
7.00 (7.50)
Month 2
2.50 (3.50)
1.50 (5.50)
5.00
Month 3
5.00 (6.00)
0
7.00 (11.50)
Month 4
5.00 (7.50)
5.50 (7.50)
4.00 (3.50)
Month 5
0.50 (7.50)
5.50 (10.50)
7.00 (7.75)
Month 6
3.00 (9.00)
3.50 (4.00)
6.00 (10.25)
Off-wall rearing
Month 1
1.50 (7.00)
3.00 (2.50)
10.00
Month 2
7.50 (7.50)
1.00 (4.50)
8.00 (9.75)
Month 3
4.00 (6.50)
0.50 (3.50)
8.00 (11.25)
Month 4
3.50 (7.50)
1.50 (6.00)
4.00 (5.00)
Month 5
3.00 (8.00)
2.50 (8.50)
3.00 (9.75)
Month 6
4.00 (9.00)
3.00 (4.00)
8.00 (11.00)
Values are median and interquartile range of cumulative spent time on these behaviors ( = 7–13). denotes differences from the control group, .
