Chronic Exposure to Arsenic in Drinking Water Causes Alterations in Locomotor Activity and Decreases Striatal mRNA for the D2 Dopamine Receptor in CD1 Male Mice
Table 3
Aggression test (intruder-resident paradigm).
Time of exposure
Control
0.5 mg As/L
5.0 mg As/L
Latency to first attack (time)
Month 1
382.25 (554.90)
600.00 (487.60)
600.00 (378.02)
Month 2
154.80 (538.55)
446.10 (447.10)
600.00 (0.00)
Month 3
178.75 (401.35)
600.00 (473.85)
600.00 (216.30)
Month 4
600.00 (283.00)
450.00 (503.90)
516.20 (371.32)
Month 5
600.00 (424.50)
600.00 (311.40)
600.00 (297.10)
Month 6
600.00 (294.55)
600.00 (419.75)
600.00 (133.27)
Frequency (counts)
Month 1
1.00 (2.50)
0 (1.50)
0 (1.00)
Month 2
1.00 (2.00)
0.50 (2.50)
0 (0)
Month 3
1.00 (0.50)
0 (1.50)
0 (1.00)
Month 4
0 (0.50)
0.50 (1.50)
1.00 (1.00)
Month 5
0 (1.50)
0 (1.00)
0 (1.25)
Month 6
0 (0.50)
0 (1.0)
0 (1.25)
Total duration of attacks (time)
Month 1
23.80 (1213.15)
0 (22.85)
0 (22.49)
Month 2
32.20 (46.20)
6.70 (99.50)
0 (0)
Month 3
11.75 (30.25)
0 (57.40)
0 (5.24)
Month 4
0 (6.80)
5.6 (22.60)
0.76 (22.37)
Month 5
0 (12.25)
0 (11.45)
0 (13.40)
Month 6
0 (8.30)
0 (11.35)
0 (3.17)
Boxing (counts)
Month 1
0 (0)
0 (2.00)
0 (1.00)
Month 2
0 (1.00)
0 (0.50)
0 (0)
Month 3
0.50 (1.00)
0 (1.00)
0 (0.25)
Month 4
0 (0)
0 (0.50)
0 (1.25)
Month 5
0 (0)
0.50 (1.00)
0 (0.25)
Month 6
0 (1.50)
0.50 (1.50)
0 (0)
Tail rattling (counts)
Month 1
0 (9.00)
0 (3.00)
0 (1.00)
Month 2
1.00 (9.50)
0.50 (4.00)
0 (0)
Month 3
4.50 (10.00)
0 (2.50)
0 (0.50)
Month 4
0 (1.50)
1.00 (3.00)
1.00 (3.25)
Month 5
0 (11.00)
0.50 (4.00)
0 (2.75)
Month 6
0 (8.00)
1.50 (9.50)
0 (2.00)
Values are median and interquartile range ( = 7–13).
