Impact of Exposure to Fenitrothion on Vital Organs in Rats

Figure 2

Effects of fenitrothion on liver histopathology in rats using H & E staining (400). C: normal hepatic parenchyma, F1: mild congested, disorganized hepatic lobules and slight cell swelling, F2: moderate cell swelling associated with apoptosis and focal necrosis, F3: moderate degenerated and ballooned necrotic hepatocytes with lymphocytic aggregation and cell infiltration, F4: severe disappearance of hepatocytes and large areas of congestion, lymphocytic aggregation, and inflammation, and F6: thickened interlobular tissue by edematous fibrous tissue and congested blood vessels. N: normal liver cells. Black star: congested cells with cytoplasmic vacuolation. Green lightning: lymphocytic aggregation. Red arrow: edematous fibrous tissue.