Possible Protective Effect of Diacerein on Doxorubicin-Induced Nephrotoxicity in Rats

Figure 1

Photomicrographs of renal cortex of (a), (b), and (c), control, DLD, and DHD groups, respectively, showing normal lobular organization of the renal cortex; normal renal glomeruli and tubules. (d) DOX treated group showing markedly enlarged and congested vascular renal glomeruli and cytoplasmic vacuolations of corpuscular cells. Inflammatory cell infiltrations are observed. (e) DOX/DLD group showing less cytoplasmic vacuolations of the renal corpuscular cells and tubular cells. (f) DOX/DHD showing apparent normal renal cortex. H&E ×400. Bar = 20 μ.

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