State of the Science: Biologically Based Modeling in Risk Assessment

• State of the Science: Biologically Based Modeling in Risk Assessment, Jane C. Caldwell, Kannan Krishnan, and Marina V. Evans
  Volume 2012 (2012), Article ID 758182, 2 pages
• Cutting Edge PBPK Models and Analyses: Providing the Basis for Future Modeling Efforts and Bridges to Emerging Toxicology Paradigms, Jane C. Caldwell, Marina V. Evans, and Kannan Krishnan
  Volume 2012 (2012), Article ID 852384, 10 pages
• Physiologically Based Pharmacokinetic (PBPK) Modeling of Metabolic Pathways of Bromochloromethane in Rats, W. S. Cuello, T. A. T. Janes, J. M. Jessee, M. A. Venecek, M. E. Sawyer, C. R. Eklund, and M. V. Evans
  Volume 2012 (2012), Article ID 629781, 14 pages
• Quantitative Property-Property Relationship for Screening-Level Prediction of Intrinsic Clearance of Volatile Organic Chemicals in Rats and Its Integration within PBPK Models to Predict Inhalation Pharmacokinetics in Humans, Thomas Peyret and Kannan Krishnan
  Volume 2012 (2012), Article ID 286079, 22 pages
• Physiologically Based Toxicokinetic Modelling as a Tool to Support Risk Assessment: Three Case Studies, Hans Mielke and Ursula Gundert-Remy
  Volume 2012 (2012), Article ID 359471, 11 pages
• Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT—Part II: Physiologically Based Pharmacokinetic Modeling and Manganese Risk Assessment, Michael D. Taylor, Harvey J. Clewell III, Melvin E. Andersen, Jeffry D. Schroeter, Miyoung Yoon, Athena M. Keene, and David C. Dorman
  Volume 2012 (2012), Article ID 791431, 17 pages
• Short Communication: Is Ethanol-Based Hand Sanitizer Involved in Acute Pancreatitis after Excessive Disinfection?—An Evaluation with the Use of PBPK Model, Céline Huynh-Delerme, Catherine Artigou, Laurent Bodin, Robert Tardif, Ginette Charest-Tardif, Cécile Verdier, Nessryne Sater, Mostafa Ould-Elhkim, and Catherine Desmares
  Volume 2012 (2012), Article ID 959070, 7 pages
• Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation, Kevin McNally, Richard Cotton, John Cocker, Kate Jones, Mike Bartels, David Rick, Paul Price, and George Loizou
  Volume 2012 (2012), Article ID 760281, 18 pages
• Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT—Part I: Program Implementation and Lessons Learned, David C. Dorman, Melvin E. Andersen, Jerry M. Roper, and Michael D. Taylor
  Volume 2012 (2012), Article ID 946742, 10 pages
• Application of Physiologically Based Pharmacokinetic Models in Chemical Risk Assessment, Moiz Mumtaz, Jeffrey Fisher, Benjamin Blount, and Patricia Ruiz
  Volume 2012 (2012), Article ID 904603, 11 pages
• Modeling the Human Kinetic Adjustment Factor for Inhaled Volatile Organic Chemicals: Whole Population Approach versus Distinct Subpopulation Approach, M. Valcke, A. Nong, and K. Krishnan
  Volume 2012 (2012), Article ID 404329, 14 pages
• Development of Screening Tools for the Interpretation of Chemical Biomonitoring Data, Richard A. Becker, Sean M. Hays, Steven Robison, and Lesa L. Aylward
  Volume 2012 (2012), Article ID 941082, 10 pages
• An In Silico Approach for Evaluating a Fraction-Based, Risk Assessment Method for Total Petroleum Hydrocarbon Mixtures, Nina Ching Y. Wang, Glenn E. Rice, Linda K. Teuschler, Joan Colman, and Raymond S. H. Yang
  Volume 2012 (2012), Article ID 410143, 8 pages
• Reconstructing Organophosphorus Pesticide Doses Using the Reversed Dosimetry Approach in a Simple Physiologically-Based Pharmacokinetic Model, Chensheng Lu and Leo Andres
  Volume 2012 (2012), Article ID 131854, 8 pages
• Bayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats, Alan F. Sasso, Panos G. Georgopoulos, Sastry S. Isukapalli, and Kannan Krishnan
  Volume 2012 (2012), Article ID 895391, 10 pages