Computational Perspectives into Plasmepsins Structure—Function Relationship: Implications to Inhibitors Design

Figure 2

Top view of the surface representation of plasmepsin II. The seven new functional residues proposed by Valiente and colleagues [5], and the catalytic aspartic residues, are shown in stick representation. The enzyme subsites, the flap, and the flexible loops L3 and L4 (identified by Bhargavi and coworkers [6]) were sketched in orange.