Research Article

Peptides Derived from Mycobacterium leprae ML1601c Discriminate between Leprosy Patients and Healthy Endemic Controls

Table 1

ML1601c synthetic peptides.

Peptide no.Amino acid sequence*Amino acid identity**

11AHHNAHAAPAFLWSGLVSA42% (8/19)
12FLWSGLVSAAVLIADGRGE52% (10/19)
13AVLIADGRGEDTYLPIISIY40% (8/20)
14DTYLPIISIYLARGNELKPN10% (2/20)
15LARGNELKPNPLLSVIYVEH25% (5/20)
16PLLSVIYVEHLLVLFYQSVG35% (7/20)
17LLVLFYQSVGDHCGFGRYDF45% (9/20)
18DHCGFGRYDFGKTMVLACYG50% (10/20)
19GKTMVLACYGCVGTRSLLSG30% (6/20)
20CVGTRSLLSGRDDDLVTSVP15% (3/20)
3RDDDLVTSVPPCGRASVVHRS0% (0/21)

*Synthetic peptides overlapping ML1601c are shown in single-letter amino acid code.
**Amino acid sequences of ML1601c (M. leprae TN and BR4923) peptides were analyzed using BLAST (http://blast.ncbi.nlm.nih.gov/); amino acids that are identical to the MAP3249 are depicted in bold.