Clinical Study

Efficacy and Tolerability of Malartin and Sulphadoxine-Pyrimethamine Combination against Uncomplicated Falciparum Malaria in Dibanda, Southwest Cameroon

Table 3

Variation in geometric mean parasite density of patients attending CAMEF during the in vivo study, 2007-2008 by sex, age group, and social class during followup after treatment with Malartin and SP.

CharacteristicGMPD
CategoryDay 0Day 3Day 7Day 14

SexMale 𝑁 = 7 4 4599 (1014–04000)2199 (382–5846)900 (207–4938)808 (280–3749)
Female 𝑁 = 1 0 0 4154 (1000–42974)1904 (196–10667)641 (143–4525)626 (167–3574)
Level of significance 𝐹 = 1 . 4 1 8
𝑃 = 0 . 2 3 5
𝐹 = 0 . 6 2 5
𝑃 = 0 . 4 3 0
𝐹 = 4 . 8 2 6
𝑃 = 0 . 0 3 0
𝐹 = 0 . 7 6 4
𝑃 = 0 . 3 8 6

Age group (years)1–5 ( 𝑁 = 4 9 )6517 (1087–48511)2189 (196–5846)788 (181–3629)751 (170–3749)
6–10 ( 𝑁 = 3 3 )3820 (1067–104000)1652 (203–7719)608 (182–1920)604 (475–776)
11–15 ( 𝑁 = 2 4 )4054 (1200–18316)2424 (333–7385)832 (207–2913)613 (167–2222)
>15 ( 𝑁 = 6 8 )3524 (1000–36596)1975 (218–10667)730 (143–4938)692 (150–3176)
Level of significance 𝐹 = 3 . 6 6 7
𝑃 = 0 . 0 1 4
𝐹 = 1 . 2 3 2
𝑃 = 0 . 3 0 0
𝐹 = 0 . 7 4 0
𝑃 = 0 . 5 4 0
𝐹 = 1 . 1 4 3
𝑃 = 0 . 3 4 2

Social classPoor class ( 𝑁 = 1 3 6 )4495 (1000–48511)2021 (203–10667)727 (143–4938)854 (167–3749)
Middle class ( 𝑁 = 3 2 )4238 (1014–104000)2239 (196–15846)838 (385–2939)746 (350–3176)
Rich class ( 𝑁 = 0 6 )2193 (1023–5500)822 (406–2016)353 (353–353)0
Level of significance 𝐹 = 0 . 7 9 3
𝑃 = 0 . 4 5 4
𝐹 = 1 . 3 1 5
𝑃 = 0 . 2 7 2
𝐹 = 0 . 2 8 2
𝑃 = 0 . 7 5 5
𝐹 = 0 . 2 3 4
𝑃 = 0 . 7 9 2