Clinical Study

Plasma Level of IL-4 Differs in Patients Infected with Different Modern Lineages of M. tuberculosis

Figure 3

Plasma cytokine and chemokine levels in TB cases infected with different strains. Plasma samples from TB cases infected with CAS ( ), H ( ), and T families ( ) were assessed by multiplex cytokine analysis. (a) Anti-inflammatory cytokines (IL-10 and IL-4), (b) growth factors (EGF and VEGF), (c) Proinflammatory cytokines (IFN-γ, IL-12 (p40), and TNF) and (d) chemokines (IP-10, MCP-1, MCP-3, MIP-1β, and fractalkine). Horizontal line indicates median levels of TB cases infected with the CAS family (filled circles), H family (open circles) and T family (filled diamonds). Data were analysed using nonparameteric Mann-Whitney test with values indicating significant differences after data were trimmed and transformed to Log2 values. * .
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(a)
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(b)
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(c)
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(d)