Plasma Level of IL-4 Differs in Patients Infected with Different Modern Lineages of M. tuberculosis
Figure 4
Th1/Th2 ratios of cytokines of TB cases infected with different strains. Box plots are shown with the horizontal line indicating median levels of TB cases and the lower and upper edges of each box indicate the 25th and 75th percentiles, respectively. (a) Ratio of Th1/Th2 cytokines (IFN-γ/IL-4, IFN-γ/IL-10, IL-12/IL-4, and IL-12/IL-10) of TB patients infected with lineage 3 (white bars), and lineage 4 (grey bars); (b) Ratio of Th1/Th2 cytokines (IFN-γ/IL-4, IFN-γ/IL-10, IL-12/IL-4, and IL-12/IL-10) of TB patients infected with CAS family (white bars) H family (grey bars), and T family (crossed bars). Data were analysed using nonparametric Mann-Whitney test with -values indicating significant differences after data were trimmed and transformed to Log 2 values. *.
