Systematic Review into Diagnostics for Post-Kala-Azar Dermal Leishmaniasis (PKDL)
Figure 2
(a) Raw ROC plot of the serological tests. Every symbol refers to the sensitivity (-axis) and specificity (-axis) of a test in a study. The height of the symbol represents the number of diseased in the study, and the width of the symbol represents the number of nondiseased in the study. Circles = DAT; diamonds = rK39 LF; squares = rK39 ELISA; triangles = other serological tests. The majority of studies are clustered into the upper hand left corner, indicating a near perfect sensitivity and specificity; however, poor patient selection must be taken into account when drawing conclusions. (b) Raw ROC plot of PCR and IHC. Every symbol refers to the sensitivity (-axis) and specificity (-axis) of a test in a study. The height of the symbol represents the number of diseased in the study, and the width of the symbol represents the number of nondiseased in the study. Circles = PCR; diamonds = IHC. The majority of studies have a sensitivity of above 90%, but specificity varies widely.
