Post-Kala-Azar Dermal Leishmaniasis: A Paradigm of Paradoxical Immune Reconstitution Syndrome in Non-HIV/AIDS Patients
Table 1
IL-2, IL-12, INF-γ, and IL-10 levels and LST induration (mm) in some patients in the study.
ID
Day 2
Day 60
Treatment outcome
IL-2
IL-12
INF-γ
IL-10
LST
IL-2
IL-12
INF-γ
IL-10
LST
110*
716
00
2505
16
00
135
4.8
438
22
07
Not healed
107*
55
2.9
2428
21
03
80
07
865
08
07
Healed
104*
1220
4.8
2349
38
03
1530
18
1342
47
11
Healed
116*
00
00
1016
33
08
34
03
968
81
10
Healed
105*
150
00
720
00
00
30
18
27
48
06
Healed
121*
00
08
00
00
00
20
04
531
22
07
Healed
123*
00
00
101
04
00
00
06
209
09
10
Healed
118*
00
02
427
12
08
00
4.8
85
36
09
Healed
129*
00
00
342
19
06
15
16.5
270
40
11
Healed
102*
00
1.8
74
00
00
42
4.8
874
35
07
Healed
112
970
06
2584
345
03
45
00
151
08
08
Healed
109
00
3.6
2584
09
00
25
05
626
17
08
Healed
108
155
00
2271
19
00
185
00
1231
00
05
Healed
106
45
4.8
2193
00
00
420
10.5
1342
29
00
Healed
103
00
3.6
1732
00
00
52
10
1342
12
06
Healed
101
25
18
1081
33
00
100
02
1342
32
00
Not healed
130
00
1.2
813
102
04
00
00
14
20
—
Not healed
115
00
00
118
113
08
23
18
704
62
12
Healed
127
00
6.0
00
46
00
00
12.9
430
65
07
Healed
Group I patients (SSG + vaccine). IFN-γ, IL-2, Il-12, and IL-10 levels are expressed in pictogram/mL; leishmanin skin test (LST) induration is expressed in mm.
