HLA-B*44 Is Associated with Dengue Severity Caused by DENV-3 in a Brazilian Population

Table 2

Correlations between the observed allelic frequencies in the LaViTE cohort and two other Brazilian datasets deposited in the dbMHC database of the NCBI, dbMHC1 (Minas Gerais, Brazil), and dbMHC2 (São Paulo, Brazil).

HLA loci	Correlation	95% CI	𝑃 value
HLA-A
LaViTE, dbMHC1	0.9776	0.9415–0.9915	<10^−12
LaViTE, dbMHC2	0.9445	0.8588–0.9788	<10^−8
HLA-B
LaViTE, dbMHC1	0.9171	0.8357–0.9591	<10^−12
LaViTE, dbMHC2	0.8223	0.6640–0.9100	<10^−8
HLA-C
LaViTE, dbMHC2	0.9114	0.7374–0.9719	<10^−5
HLA-DR
LaViTE, dbMHC2	0.7977	0.4401–0.9368	<0.05

HLA: human leukocyte antigen; CI: confidence interval.