Clinical Study

Effectiveness and Safety of Concurrent Use of First-Line Antiretroviral and Antituberculous Drugs in Rwanda

Table 3

Association between various factors and clinical outcomes.

VariableHIV-alone ( )HIV/TB ( )
ImprovedUnimprovedDiedSignImprovedUnimprovedDiedSign
(%) (%) (%) value (%) (%) (%) value

Gender
 Male17 (89.5)02 (10.5)0.1167 (26.9)10 (38.5)9 (34.6)0.037
 Female30 (73.2)8 (19.5)3 (7.3)16 (47.1)15 (44.1)3 (8.8)
Age (years)
 <4036 (83.7)2 (4.7)5 (11.6)0.00421 (39.6)22 (41.5)10 (18.9)0.782
 >4011 (64.7)6 (35.3)02 (28.6)3 (42.9)2 (28.6)
Weight (kg)
 Gained5 (100)000.0090000.032
 Lost42 (83.3)8 (4.8)5 (11.9)23 (38.3)25 (41.7)12 (20.0)
CD4 (cells/mm3)
 Gained42 (76.4)8 (14.5)5 (9.1)0.0013 (27.3)5 (45.4)3 (27.3)0.000
 Lost4 (100)0020 (40.8)20 (40.8)9 (18.4)
ART length
 <1 year9 (75.0)03 (25.0)0.1076 (100)000.003
 1–5 years25 (78.2)5 (15.6)2 (6.2)11 (36.7)10 (33.3)9 (30.0)
 >5 years13 (81.2)3 (18.8)06 (25.0)15 (62.5)3 (12.5)
Column percent47  (78.4)8  (13.3)5  (8.3)23  (38.4)25  (41.6)12  (20)

Total between row percentage is calculated by dividing the frequency by 60 patients in each group. Within row percentage is calculated by dividing the frequency by the total frequency of each regimen alone. Sign: Pearson Chi-square.