Review Article
Antibiotic Resistance in Streptococcus pneumoniae after Azithromycin Distribution for Trachoma
Table 1
Characteristics of included studies.
| Source | Country | Treatment group | Age range | Numbers treated | Control group | Treatment frequency | Measures baseline | Follow-up | Sample population | Test kit for resistance |
|
Leach et al. 1997 [16] | Australia | Children with trachoma and their household contacts who were children | <15 years old | 130 | No | Single | Yes | 2-3 weeks; 2 months; 6 months | All children <15 years old with trachoma | E-test© strips |
| Fry et al. 2002 [17] | Nepal | All children | 1–10 years old | 169 | No | Single | Yes | 10 days; 180 days | Randomly selected 1–10-year-old children | — |
| Batt et al. 2003 [18] | Tanzania | All nonpregnant individuals | >1 year old | 4782 | No | Single | Yes | 2 months; 6 months | All children <7 year old | E-test© strips |
| Gaynor et al. 2003 [19] | Nepal | All children with clinically active trachoma and all household members of these children | 1–10 years old | 94 | No | Single | No | 1 year | Randomly selected 1–10-year-old children | E-test© strips |
| Gaynor et al. 2005 [20] | Nepal | All children | 1–10 years old | 194 | Yes | Annual ×3 | No | 6 months | All children aged 1–7 years | Sensititre© MIC plates |
| Haug et al. 2010 [21] | Ethiopia | All nonpregnant individuals | >1 year old | Not known | Yes | Biannual ×6 | No | 6 months; 12 months; 24 months | Randomly selected 1–5-year-old children | Sensititre© MIC plates |
| Skalet et al. 2010 [22] | Ethiopia | All children | 1–10 years old | 3830 | Yes | Quarterly ×4 | Yes | 3 months | Randomly selected <10-year-old children | E-test© strips |
| Coles et al. 2013 [23] | Tanzania | All children in MDA villages | <5 years old | 467 | Yes | Single | Yes | 1 month; 3 months; 6 months | Randomly selected 2–5-year-old children | E-test© strips |
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