Safety and Immunogenicity of Pertussis Vaccine Immunization during Pregnancy: A Meta-Analysis of Randomized Clinical Trials

Table 2

Meta-analysis results of GMCs for pertussis antibodies before and after primary vaccination of infants.

	Study number	Pooled SMD (95% CI)	value	I^2 (%)	Effect model
Before primary vaccination
Anti-PT	4	0.75 (0.28, 1.22)	0.002	86.3	Random
Anti-FHA	3	0.90 (0.41, 1.39)	<0.0001	80.9	Random
Anti-PRN	4	1.37 (0.90, 1.83)	<0.0001	84.0	Random
After primary vaccination
Anti-PT	4	−0.016 (−0.32, −0.01)	0.059	0	Fixed
Anti-FHA	3	−0.20 (−0.39, −0.01)	0.039	10.8	Fixed
Anti-PRN	4	−0.05 (−0.50, 0.40)	0.819	85.7	Random