Research Article
Japanese Encephalitis Vaccine Generates Cross-Reactive Memory T Cell Responses to Zika Virus in Humans
Table 1
Results of complete blood count and JEV antibody testing/titration of subjects in this study.
| | No. | Parameter | | CRP (mg/L) | WBC count (×109/L) | RBC count (×1012/L) | Hgb (g/L) | Plt count (×109/L) | NEUT count (×109/L) | LYMPH count (×109/L) | MONO count (×109/L) | EO count (×109/L) | BASO count (×109/L) | JEV IgG | JEV nAb |
| | Reference interval (2 y–<6 y) | <8 | 4.4–11.9 | 4.0–5.5 | 112–149 | 188–472 | 1.2–7 | 1.8–6.3 | 0.12–0.93 | 0–0.68 | 0–0.1 | | | | VAC 1 | <8 | 5.94 | 4.21 | 120 | 274 | 1.49 | 3.92 | 0.38 | 0.13 | 0.02 | + | 1 : 80 | | VAC 2 | <8 | 7.13 | 4.13 | 116 | 372 | 3.78 | 2.64 | 0.53 | 0.13 | 0.05 | + | 1 : 160 | | VAC 3 | <8 | 9.84 | 4.46 | 119 | 348 | 6.93 | 2.41 | 0.49 | 0 | 0.01 | + | 1 : 20 | | VAC 4 | <8 | 7.97 | 4.57 | 126 | 351 | 2.52 | 4.79 | 0.57 | 0.06 | 0.03 | + | >1 : 160 | | VAC 5 | <8 | 5.62 | 4.3 | 122 | 312 | 1.68 | 3.33 | 0.38 | 0.17 | 0.06 | + | 1 : 80 | | VAC 6 | <8 | 6.87 | 4.7 | 126 | 400 | 1.62 | 4.54 | 0.55 | 0.13 | 0.03 | + | 1 : 40 | | VAC 7 | <8 | 6.53 | 4.38 | 123 | 253 | 1.48 | 4.21 | 0.73 | 0.1 | 0.01 | + | 1 : 80 | | VAC 8 | <8 | 5.29 | 4.15 | 120 | 275 | 1.64 | 3.1 | 0.38 | 0.14 | 0.03 | + | 1 : 80 | | VAC 9 | <8 | 6.65 | 4.5 | 131 | 338 | 2.09 | 3.67 | 0.74 | 0.12 | 0.03 | + | 1 : 80 | | VAC 10 | <8 | 8.53 | 4.9 | 129 | 371 | 3.63 | 4.32 | 0.43 | 0.11 | 0.04 | + | 1 : 80 | | VAC 11 | <8 | 7.87 | 4.97 | 134 | 359 | 3.15 | 3.99 | 0.55 | 0.15 | 0.03 | + | 1 : 160 | | VAC 12 | <8 | 5.39 | 4.67 | 123 | 226 | 2.78 | 2.2 | 0.33 | 0.06 | 0.02 | + | 1 : 40 | | VAC 13 | <8 | 6.08 | 4.9 | 129 | 304 | 1.51 | 3.77 | 0.47 | 0.3 | 0.03 | + | 1 : 80 | | VAC 14 | <8 | 7.09 | 4.14 | 113 | 361 | 3.24 | 3.09 | 0.55 | 0.18 | 0.03 | + | >1 : 160 | | VAC 15 | <8 | 8.49 | 5.01 | 141 | 281 | 2.14 | 5.73 | 0.42 | 0.16 | 0.04 | + | 1 : 20 | | VAC 16 | <8 | 8.46 | 4.41 | 116 | 326 | 3.66 | 4.25 | 0.53 | 0.01 | 0.01 | + | 1 : 80 | | VAC 17 | <8 | 8.6 | 4.85 | 130 | 271 | 1.77 | 6.22 | 0.51 | 0.06 | 0.04 | + | 1 : 160 | | VAC 18 | <8 | 10.88 | 5.05 | 134 | 313 | 5.36 | 5.6 | 0.66 | 0.17 | 0.09 | + | >1 : 160 | | Mean ± standard | — | 7.4 ± 1.55 | 4.57 ± 0.32 | 125.11 ± 7.36 | 324.17 ± 60.26 | 2.8 ± 1.49 | 3.99 ± 1.12 | 0.51 ± 0.12 | 0.12 ± 0.07 | 0.03 ± 0.02 | | |
| | Reference interval (28 d–< 6 m) | <8 | 4.3–14.2 | 3.3–5.2 | 97–183 | 183–614 | 0.6–7.5 | 2.4–9.5 | 0.15–1.56 | 0.07–1.02 | 0–0.1 | | | | UNV 1 | <8 | 9.87 | 3.54 | 99 | 292 | 4.79 | 3.9 | 1.02 | 1.02 | 0.07 | − | <1 : 10 | | UNV 2 | <8 | 8.62 | 4.65 | 138 | 257 | 6.92 | 3.97 | 0.72 | 0.08 | 0.01 | − | <1 : 10 | | UNV 3 | <8 | 11.5 | 5.1 | 169 | 377 | 5.62 | 5.81 | 1.23 | 0.38 | 0.03 | − | <1 : 10 | | UNV 4 | <8 | 9.47 | 3.65 | 125 | 405 | 2.6 | 4 | 1.08 | 0.77 | 0.02 | − | <1 : 10 | | UNV 5 | <8 | 10.95 | 4.92 | 172 | 302 | 4.7 | 3.96 | 1.01 | 0.36 | 0.04 | − | <1 : 10 | | UNV 6 | <8 | 6.4 | 3.57 | 109 | 258 | 0.67 | 3.86 | 0.6 | 0.26 | 0.01 | − | <1 : 10 | | UNV 7 | <8 | 5.87 | 3.88 | 112 | 247 | 1.50 | 3.61 | 0.56 | 0.08 | 0.02 | − | <1 : 10 | | Mean ± standard | — | 8.95 ± 2.15 | 4.19 ± 0.68 | 132 ± 29.07 | 305.43 ± 62.23 | 3.83 ± 2.29 | 4.16 ± 0.74 | 0.89 ± 0.26 | 0.42 ± 0.35 | 0.03 ± 0.02 | | |
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BASO: basophil, CRP: C-reaction protein, EO: eosinophil, Hgb: hemoglobin, LYMPH: lymphocyte, MONO: monocyte, NEUT: neutrophil, Plt: platelet, RBC: red blood cell, UNV: unvaccinated individuals, VAC: vaccinated individuals, and WBC: white blood cell.
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