Research Article
Increasing Incidence, but Lack of Seasonality, of Elevated TSH Levels, on Newborn Screening, in the North of England
Table 1
TSH newborn screening base, assay methodology, and cut-off values during the study period.
| | 1994–March 1998 | April 1998–February 2003 | March 2003–March 2005 | April 2005–present |
| Centre | Newcastle | Durham | Durham | Newcastle | Method | Radioimmunoassay | ACS-180 | DELFIA | DELFIA | (Manual) | (Bayer) | (Perkin Elmer) | (Perkin Elmer) | TSH cut-off (mU/L) | 20 | 10 | 6 | 6 |
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