Thyroid Hormone and the Neuroglia: Both Source and Target

Figure 2

LPS-induced infection downregulates TRH mRNA expression in the hypothalamic paraventricular nucleus of wildtype but in D2 knock-out mice. (a,b), wild-type; (c,d), D2 KO mice; (a,c), control; (b,d), i.p. LPS-treated animals; (e), quantification of the TRH mRNA signal by densitometry. Printed from Freitas et al. American Society for Clinical Investigation [23].