The Central Effects of Thyroid Hormones on Appetite

Figure 3

Effect and consequences of fasting on central T3 levels, mediated by D2 and D3. PVN: paraventricular nucleus; ARC: arcuate nucleus; VMN: ventromedial nucleus; TRH: thyrotropin releasing hormone; T4: thyroxine; T3: triiodothyronine; OATP1C1: Organic anion transporting polypeptide 1c1; MCT8: monocarboxylate transporter 8; D2: Deiodinase 2; D3: deiodinase 3; NPY: Neuropeptide Y; AgRP: agouti-related protein; UCP2: uncoupling protein 2.