Case Report

A Patient with Postpartum Hypopituitarism (Sheehan's Syndrome) Developed Postpartum Autoimmune Thyroiditis (Transient Thyrotoxicosis and Hypothyroidism): A Case Report and Review of the Literature

Table 3

Endocrine studies at 6 months post partum.
(a) Urinary cortisol (studied one week after discontinuation of hydrocortisone)

(Normal references)

Urinary cortisol nmol/day<18 (30–230)

(b) CRH, TRH, and GnRH tests (CRH, TRH, and GnRH tests were done separately)

0 min30 min60 min90 min120 minResponse

CRH test (studied one week after discontinuation of hydrocortisone)
 ACTH pmol/L<0.4<0.4<0.4<0.4<0.4No
 Cortisol nmol/L<5.5<5.5<5.5<5.5<5.5No
TRH test
 TSH mIU/L17.438.152.957.157.7Delayed
 Prolactin pmol/L43.5178.3160.9165.2139.1Low
GnRH test
 LH IU/L0.56.611.113.113.7Delayed
 FSH IU/L2.22.63.33.94.3Delayed

Normal references for basal ACTH, cortisol, TSH, prolactin, LH, and FSH appear in Table 2.
(c) Insulin tolerance test (ITT) for GH releases

−30 min0 min30 min60 min90 min120 min

GH μg/L1.01.10.84.13.82.5
BG nmol/L4.64.32.23.13.74.3

BG: blood glucose. Normal references for basal GH appear in Table 2.
(d) ADH (antidiuretic hormone), plasma osmolality, and urine osmolality at 9:00

(Normal references)

Plasma ADH pmol/L0.92 (0.28–3.23)
Plasma osmolality mmol/kg287 (285–293)
Urine osmolality mmol/kg767 (300–900)