TRAb assays compared after 18 months of treatment: 3-year followup
0.94–3.2 IU/L
48
53–66%
Most recent studies are small and retrospective. They were variable in their study design (e.g., timing of TRAb measurement), assay methodology and TRAb cutoff values used for analysis, and population characteristics (i.e., geographically disparate). Although there was a high relapse rate (45–71.8%), TRAb assay by itself had a poor PPV and was a poor predictor of relapse even when different cutoff values were used.