Review Article

Thyroid Surgery for Elderly Patients: Are They at Increased Operative Risks?

Table 1

A comparison of patient characteristics, definitions, indications, and procedures between different elderly surgical series.

Study/yearDesignDefinition of “elderly” (years)Number of patients (%)IndicationsTypes of procedure

Bliss et al.
[3]
(1999)
Retrospective(1) Elderly ≥75
(2) 61–74
(3) 50–60
(1) 221 (13.5)
(2) 685 (42.1)
(3) 725 (44.4)
(i) Compression symptoms(i) Total thyroidectomy
(ii) Risk of malignancy(ii) Hemithyroidectomy
(iii) Hyperparathyroidism(iii) Total Lobectomy & subtotal  thyroidectomy
(iv) Retrosternal goiter *(iv) Bilateral subtotal thyroidectomy
(v) Toxic symptoms(v) Enucleation of nodule
(vi) Completion(vi) Isthmectomy
(vii) Others(vii) Others

Passler et al. [16]
(2002)
Retrospective (1) Geriatric ≥ 75
(2) Younger < 75
(1) 55 (7.5)
(2) 683 (92.5)
(i) Benign *
(ii) Suspected malignancy
(iii) Malignancy
(iv) Mechanical symptoms
(i) Radical—total/near-total thyroidectomy/hemithyroidectomy/neck dissection
(ii) Nonradical—Enucleation/unilateral subtotal/bilateral thyroidectomy/hemithyroidectomy with contralateral subtotal resection

Lang and Lo [5]
(2005)
Retrospective (1) Elderly ≥ 70
(2) Young < 70
(1) 55 (18.5)
(2) 242 (81.5)
(i) Compression symptoms (i) Total thyroidectomy
(ii) Near-total thyroidectomy
(ii) Thyrotoxicosis *
(iii) Recent enlargement *
(iv) Cosmesis /patient request *
(v) Suspicious FNAC

Sosa et al.
[6]
(2008)
Cross sectional (population based)(1) Superelderly ≥ 80(1) 744 (3.3)*NA(i) Subtotal /total thyroidectomy *
(2) Elderly 65–79(2) 4092 (17.9)*(ii) Substernal thyroid ectomy *
(3) 45–64(3) 9959 (43.6)
(4) 18–44(4) 8053 (35.2)

Mekel et al. [15]
(2009)
Retrospective (1) Octogenarian ≥ 80
(2) 18–79
(i) Benign(i) Lobectomy/partial thyroidectomy
(1) 90 (2.5)(ii) Malignancy(ii) Total/subtotal thyroidectomy
(2) 250 (randomly selected)(iii) Microfollicular
(iv) Previous thyroid surgery

Grogan et al. [4]
(2012)
Prospective cohort (population based)(1) Superelderly ≥ 80(1) 199 (2.51)NA(i) Total thyroidectomy
(2) Elderly 65–79(2) 1322 (16.7)(ii) Lobectomy
(3) 16–64(3) 6394 (80.8)(iii) Completion
(iv) With neck dissection
(v) Substernal goite cervical approach
(vi) Substernal goiter thoracic approach

Syebt et al. [10]
(2012)
Prospective non-randomized (1) Elderly > 65
(2) Young 21–35
(1) 44 (10.7)
(2) 86 (20)
(i) Benign
(ii) Malignancy
(i) Conventional thyroidectomy
(ii) Minimally invasive open  thyroidectomy
(iii) Endoscopic thyroidectomy

*Statistically significant ( 𝑃 < 0 . 0 1 ).