Association between TSH-Receptor Autoimmunity, Hyperthyroidism, Goitre, and Orbitopathy in 208 Patients Included in the Remission Induction and Sustenance in Graves’ Disease Study
Table 1
Characteristics of patients included in RISG1.
Aalborg
Copenhagen
All
Participants, (%)
167 (80.3)
41 (19.7)
208 (100)
—
Sex, F/M (% F)
138/29 (82.6)
38/3 (92.7)
176/32 (84.6)
0.15
Age years, median (IQR)
44 (34–53)
47 (36–55)
45 (35–53)
0.55
Previously hyperthyroid, (%)
12 (7.2)**
0 (0)
12 (5.8)
—
Smoker, (%)
45 (26.9)
11 (26.8)
56 (26.9)
1.00
Estrogen use, (%)
29 (21.0)
3 (7.9)
32 (18.2)
0.93
GD in 1st generation relatives, (%)
42 (25.3)*
11 (26.8)
53 (25.5)
0.87
Body height cm, median (IQR)
168 (163–173)
167 (162–172)
168 (163–172)
0.25
Body weight kg, median (IQR)
65.3 (57.8–78.1)
60.0 (53.5–68.5)
64.5 (57.5–75.9)
0.007
BMI kg/m2, median (IQR)
23.5 (21.1–26.2)
22.0 (19.9–23.8)
22.9 (20.8–26.0)
0.011
Graves’ orbitopathy, (%)
51 (30.5)
5 (12.2)
56 (26.9)
0.018
S-T4 nmol/L, median (IQR)
213 (177–269)
189 (167–238)
201 (175–255)
0.086
S-T3 nmol/L, median (IQR)
5.5 (4.3–7.5)
5.0 (3.5–6.3)
5.4 (4.2–7.1)
0.021
S-TRAb IU/L, median (IQR)
9.1 (5.1–14)
9.7 (5.4–22)*
9.1 (5.2–15.2)
0.37
S-TPO kU/L, median (IQR)
277 (33–2295)
230 (30–3600)***
266 (30–2717)
0.80
Thyroid volume mL, median (IQR)
21.1 (15.8–34.3)*
16.0 (10.0–24.0)*
20.0 (14.5–31.9)
<0.001
for comparison between Aalborg and Copenhagen participants using Mann-Whitney test or the Pearson /Fisher’s exact test as appropriate. F: female. M: male. IQR: 25–75% interval. GD: Graves’ disease.
*One value missing.
**Two values missing.
***Three values missing.
