Cardiovascular Risk Factors in Subclinical Hypothyroidism: A Case Control Study in Nepalese Population

Table 1

Characteristics of the study subjects.

Variables	Subclinical hypothyroid (SH) (cases) ()				Euthyroid; (controls); ()	value; (total)
	SH with TSH <10 mIU/L; ()	SH with TSH ≥10 mIU/L; ()	value	Total ()
Age (years)	42.23 ± 11.15	38.60 ± 10.07	0.202	41.14 ± 10.92	41.14 ± 10.92	1.0
BMI (Kg/m^2)	23.87 ± 1.91	26.01 ± 2.51	<0.001	24.51 ± 2.32	24.11 ± 1.66	0.422
Systolic BP (mmHg)	119.6 ± 5.98	124.2 ± 6.37	<0.001	120.98 ± 6.42	121.46 ± 6.06	0.457
Diastolic BP (mmHg)	80.66 ± 5.86	85.4 ± 5.09	<0.001	82.08 ± 6.03	79.12 ± 6.05	<0.001
Free T3 (pmol/L)	4.82 ± 0.48	4.32 ± 0.3	<0.001	4.67 ± 0.49	5.11 ± 0.58	<0.001
Free T4 (pmol/L)	10.54 ± 0.85	9.47 ± 0.28	<0.001	10.22 ± 0.88	12.06 ± 2.0	<0.001
TSH (mIU/L)	7.73 ± 1.14	14.09 ± 3.48	<0.001	9.63 ± 3.61	2.35 ± 1.07	<0.001
Total cholesterol (mg/dL)	191.74 ± 28.76	217.83 ± 30.74	<0.001	199.57 ± 31.58	184.27 ± 30.8	<0.001
LDL-C (mg/dL)	96.54 ± 24.32	121.5 ± 26.88	<0.001	104.03 ± 27.5	94.58 ± 25.43	0.004
HDL-C (mg/dL)	45.89 ± 7.88	45.93 ± 7.58	0.97	45.9 ± 7.76	47.43 ± 6.84	0.203
TC/HDL-C	4.33 ± 1.16	4.9 ± 1.26	0.015	4.5 ± 1.22	3.98 ± 0.99	<0.001
LDL-C/HDL-C	2.19 ± 0.79	2.74 ± 0.93	0.001	2.36 ± 0.87	2.05 ± 0.69	0.002
hs-CRP (mg/L)	0.64 (0.34, 1.36)	2.31 (1.19, 5.52)	<0.001	0.83 (0.43–2.3)	0.55 (0.33–1.35)	0.009

Data is expressed as mean ± SD, except for hs-CRP level. value was calculated at 95% confidence interval.