De Novo Donor-Specific HLA Antibody Development and Peripheral CD4⁺CD25^high Cells in Kidney Transplant Recipients: A Place for Interaction?

Figure 2

(a) Graft survival according to DSA development during the first year post-KT; DSA+ve versus DSA−ve, 𝑃=0.021. (b) Graft survival according to class I DSA development during the first year post-KT, 𝑃=0.079. Treg numbers (c) and percentages (d) at different time points during the first year post-KT in patients who developed DSA and those who remained DSA−ve. At 12 months, the difference in Treg numbers and percentages was significantly different between DSA+ve versus DSA−ve patients, 𝑃=0.048, and 𝑃=0.026, respectively.

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