Thymoglobulin Induction Dosing Strategies in a Low-Risk Kidney Transplant Population: Three or Four Days?

Table 1

Recipient and Donor Characteristics.

Recipient Characteristics	1.5 mg/kg x 4 days ($n=59$)	2 mg/kg x 3 days ($n=59$)	$P$ value
Age, yrs	$52\pm 13$	$49\pm 13$	.136
% of Patients >60 yrs, Number (%)	22 (37%)	16 (27%)	.237
Race, Number (%)			.490
White	46 (78%)	44 (75%)
Black	12 (20%)	11 (19%)
Gender, Number (%)			.456
Female	23 (39%)	27 (46%)
Weight (kg)	$84\pm 18$	$79\pm 21$	.215
Body Mass Index (kg/m^2)	$28\pm 5$	$27\pm 7$	.566
Transplant Type, Number (%)			.353
Deceased Donor	31 (53%)	36 (61%)	.559
Expanded Criteria Donor	9 (15%)	1 (2%)	.008
Pretransplant Dialysis	43 (73%)	44 (75%)	.834
Transplant Number, Number (%)
First	57 (97%)	58 (98%)	.559
Cause of Renal Disease, Number (%)			.572
Hypertension	22 (37%)	14 (24%)
Diabetes	10 (17%)	10 (17%)
Polycystic Kidney Disease	10 (17%)	9 (15%)
Glomerulonephritis	10 (13%)	14 (24%)
Lupus	1 (2%)	3 (5%)
Other	6 (10%)	9 (15%)
Donor Age	$39\pm 14$	$37\pm 11$	.412
CMV Serostatus Donor/Recipient, Number (%)			.381
Negative/negative	8 (14%)	10 (17%)
Positive/negative	16 (27%)	9 (15%)
Negative/positive	17 (29%)	16 (27%)
Positive/positive	18 (31%)	24 (41%)
Class I antibody, Number (%)	6 (10%)	14 (24%)	.050
Class II antibody, Number (%)	9 (15%)	7 (12%)	.590
Cold Ischemia Time, (hrs)	$11\pm 5$	$13\pm 6$	.110
Delayed Graft Function, Number (%)	4 (7%)	5 (8%)	.729

Mean ± SD.
Abbreviations: ESRD: end stage renal disease, CMV: cytomegalovirus.