Thymoglobulin Induction Dosing Strategies in a Low-Risk Kidney Transplant Population: Three or Four Days?

Table 2

Outcomes.

	1.5 mg/kg $\times$ 4 days ($n=59$)	2 mg/kg $\times$ 3 days ($n=59$)	$P$ value
Patient Survival, #(%)	57 (97%)	59 (100%)	.317
Graft Survival, #(%)	54 (92%)	56 (95%)	.766
Freedom from Rejection, #(%)	56 (95%)	56 (95%)	.983
Grade of Rejection, #(%)
Grade I	3	2
Grade II	0	0
Grade III	0	1
Infection #${(\%)}^{*}{\hspace{0.17em}}^{\hspace{0.17em}}$	7 (12%)	12 (20%)	.142
Viral	2	3
Fungal	0	1
Bacterial	6	8
Site
Blood	5	5
Urine	1	1
Skin and Soft Tissue	1	3
Lung	0	1
Other/ Unknown	1	2
PTLD, #(%)	0 (0%)	0 (0%)
Tumor, #(%)	3 (5%)	1 (2%)	.309
CMV Infection, #(%)	1 (2%)	2 (3%)	.154
Length of Stay (days)	$6.0\pm 3.7$	$5.1\pm 1.9$	.104
Serum Creatinine (mg/dL)
Baseline	$7.6\pm 3.3$	$8.4\pm 3.6$	.207
6 months	$1.4\pm 0.4$	$1.3\pm 0.4$	.383
12 months	$1.4\pm 0.5$	$1.4\pm 0.5$	.748
Last followup	$1.6\pm 1.3$	$1.6\pm 0.9$	.898
GFR (mg/mL)
Baseline	$10\pm 5$	$10\pm 7$	.766
6 months	$67\pm 29$	$69\pm 22$	.646
12 months	$68\pm 37$	$67\pm 23$	.867
Last followup	$65\pm 39$	$68\pm 23$	.642
Total Dose (mg)	$474\pm 132$	$450\pm 119$	.308
rATG Doses (#)	$3.7\pm 0.7$	$3.0\pm 0.5$

Mean ± SD.
Abbreviations: PTLD, posttransplant lymphoproliferative disorder, CMV, cytomegalovirus, GFR, glomerular filtration rate.
${}^{*}$One patient had a bacterial and viral infection.