Review Article

Approach to the Pretransplant Evaluation of the Living Kidney Donor

Table 1

Summary of pretransplant donor evaluation.

Donor screening componentsRationale

Screening to Protect the Donor
Medical
 General medical/Cardiac preop assessmentPerioperative and long-term risks
 Diabetes MellitusRisk of chronic kidney disease, cardiovascular disease
 HypertensionRisk of chronic kidney disease, cardiovascular disease
 AgeRisk of chronic kidney disease
 PregnancyRick of complications during pregnancy
Renal
 Glomerular filtration rateRisk of chronic kidney disease
 ProteinuriaRisk of chronic kidney disease
 HematuriaRisk of chronic kidney disease
 NephrolithiasisRisk of kidney disease (acute and chronic)
Lifestyle
 Overweight and obesityMetabolic, cardiovascular risks
 SmokingCardiovascular and possible renal risks
 Assessment for high risk behaviorsLong-term medical risks
Psychosocial
 Psychosocial and psychiatric issuesShort term and long-term exacerbation
 Informed consentRisks related to not understanding, coercion

Donor screening to protect the recipient
Medical
  InfectionRisk of transmission of infection to recipient
   MalignancyRisk of transmission of malignancy to recipient
RenalRisk of donor derived kidney disease
Lifestyle
 Assessment for high-risk behaviorsPotential for transmission of an unidentified infectious agent