Research Article
Intraoperative Hyperglycemia Augments Ischemia Reperfusion Injury in Renal Transplantation: A Prospective Study
(a) Percentage change in creatinine on post-operative day two. |
| Characteristic | β Coefficient | 95% Confidence interval | -value |
| Recipient age (per 10 years) | 0.05 | −0.02 to 0.11 | 0.15 | Recipient gender (male) | 0.11 | −0.05 to 0.27 | 0.18 | Recipient race (compared to white) | | | | Black | 0.02 | −0.23 to 0.26 | 0.88 | Hispanic | −0.21 | −0.29 to 0.02 | 0.03 | Asian/Pacific Islander | −0.14 | −0.51 to 0.22 | 0.43 | Blood glucose (per 10 unit increase) | 0.02 | 0.001 to 0.03 | 0.04 | Blood glucose > 160 mg/dL | 0.20 | 0.02 to 0.39 | 0.03 | Recipient diabetes | 0.16 | 0.001 to 0.32 | 0.05 | Panel reactive antibody | −0.26 | −0.58 to 0.05 | 0.10 | Recipient body mass index | 0.02 | 0.01 to 0.04 | <0.01 | Warm ischemic time (>30 min) | 0.32 | 0.16 to 0.48 | <0.01 | Intra-operative IVF (per liter) | 0.09 | −0.01 to 0.20 | 0.09 | Thymoglobulin induction (compared to simulect) | −0.20 | −0.37 to -0.02 | 0.03 | Donor age (per 10 years) | 0.09 | 0.02 to 0.16 | 0.02 | Donor gender (male) | −0.02 | −0.15 to 0.11 | 0.79 | Donor race (compared to caucasian) | | | | Black | 0.04 | −0.21 to 0.30 | 0.74 | Hispanic | −0.15 | −0.35 to 0.05 | 0.13 | Asian/Pacific Islander | −0.08 | −0.40 to 0.24 | 0.61 | Donor BMI | 0.002 | −0.02 to 0.03 | 0.84 |
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(b) Multivariate model of percentage change in creatinine on post-operative day two. |
| Characteristic | β Coefficient | 95% Confidence interval | -value |
| Blood glucose > 160 mg/dL | 0.16 | 0.02 to 0.30 | 0.03 | Warm ischemic time (>30 min) | 0.23 | 0.07 to 0.40 | <0.01 | Recipient age (per 10 years) | 0.06 | 0.002 to 0.1 | 0.04 | Recipient BMI | 0.01 | −0.001 to 0.03 | 0.07 |
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