Clinical Study

Perioperative Minimal Induction Therapy: A Further Step toward More Effective Immunosuppression in Transplantation

Table 1

Baseline characteristics of donors and recipients.

Overall ( š‘› = 7 5 )Patients ( š‘› = 2 5 )Reference-patients ( š‘› = 5 0 )

Donors
ā€ƒMales (%)37 (49.3)12 (48)25 (50)
ā€ƒAge (yrs) 4 8 . 0 Ā± 1 3 . 1 4 6 . 9 Ā± 1 1 . 8 4 8 . 9 Ā± 1 3 . 8
ā€ƒWeight (Kg) 7 2 . 0 Ā± 1 4 . 6 7 3 . 3 Ā± 1 6 . 9 7 1 . 3 Ā± 1 3 . 5
Mismatches
ā€ƒA 0 . 9 Ā± 0 . 6 0 . 8 Ā± 0 . 8 0 . 9 Ā± 0 . 5
ā€ƒB 1 . 3 Ā± 0 . 7 1 . 0 Ā± 0 . 6 * 1 . 4 Ā± 0 . 7
ā€ƒDR 1 . 2 Ā± 0 . 6 1 . 0 Ā± 0 . 6 1 . 2 Ā± 0 . 6
Recipients
ā€ƒMales (%)48 (64)16 (64)32 (64)
ā€ƒAge (yrs) 4 9 . 3 Ā± 1 0 . 9 5 1 . 5 Ā± 1 1 . 4 4 8 . 2 Ā± 1 0 . 6
ā€ƒWeight (Kg) 6 7 . 4 Ā± 1 3 . 5 7 0 . 7 Ā± 1 4 . 3 * 6 5 . 7 Ā± 1 2 . 9
ā€ƒCold ischemia time (h) 1 4 . 7 Ā± 7 . 1 1 5 . 7 Ā± 6 . 9 1 4 . 3 Ā± 7 . 2
Causes of ESRD
ā€ƒHypertension, renovascular disease4 (5.3%)3 (12%)1 (2%)
ā€ƒGlomerulonephritis20 (26.7%)7 (28%)13 (26%)
ā€ƒPolycystic kidney disease12 (16%)4 (16%)8 (16%)
ā€ƒOther18 (24%)7 (28%)11 (22%)
ā€ƒUnknown21 (28%) 4 (16%)17 (34%)

Data are numbers (percent) or mean Ā± SD. * š‘ƒ < 0 . 0 5 versus reference-patients.