Pretransplant Fasting Glucose Predicts New-Onset Diabetes after Liver Transplantation
Table 1
Pretransplant demographics by development of NODAT.
NODAT−
NODAT+
Total
value
Recipient age, years
51.7 ± 10.4
51.2 ± 5.9
51.7 ± 9.8
0.76
Male gender, (%)
127 (68.3)
33 (84.6)
160 (71.1)
0.04
Recipient race, (%)
0.83
Caucasian
140 (75.2)
30 (76.9)
170 (76.6)
Hispanic
31 (16.7)
6 (15.4)
37 (16.4)
Other
12 (6.5)
2 (5.6)
14 (6.3)
Family history of DM, (%)
58 (31.7)
16 (43.2)
74 (33.6)
0.17
Etiology of liver disease
0.001
HCV, (%)
82 (44.1)
29 (74.3)
111 (49.3)
ALD, (%)
29 (15.6)
2 (5.1)
31 (13.8)
Other
75 (40.3)
8 (20.5)
83 (36.9)
LDLT, (%)
41 (22.0)
2 (5.1)
43 (19.1)
0.02
Calculated MELD
18.7 ± 8.5
18.5 ± 7.9
18.7 ± 8.4
0.88
BMI
27.8 ± 5.2
29.2 ± 5.1
28.1 ± 5.2
0.13
Obese (BMI ≥ 30)
71 (38.1)
17 (43.6)
88 (39.1)
0.4
Morbid obesity (BMI ≥ 40)
4 (2.1)
1 (2.6)
5 (2.2)
0.02
Pre-tx FPG (mg/dL)
91 ± 8
97 ± 10
92 ± 9
0.0001
Pre-tx IFG N (%)
16 (8.6)
8 (20.5)
24 (10.7)
0.03
Pre-tx cholesterol (mg/dL)
135 ± 107
113 ± 44
132 ± 99
0.21
Pre-tx triglycerides (mg/dL)
89 ± 51
92 ± 49
89 ± 51
0.74
Donor demographics
Male gender, N (%)
109 (58.6)
27 (69.2)
136 (60.4)
0.22
BMI, mean
26 ± 5.0
26.8 ± 5.7
26.1 ± 5.1
0.41
Age, years
40.1 ± 16.4
37.9 ± 16.3
39.7 ± 16.3
0.44
Hispanic race, N (%)
36 (19.3)
14 (35.9)
50 (22.2)
0.02
Continuous variables presented as means with standard deviations. ALD: alcoholic liver disease, BMI: body mass index, DM: diabetes mellitus, FPG : fasting plasma glucose, HCV: hepatitis C virus, IFG: impaired fasting glucose, LDLT: living-donor liver transplantation, MELD: model for end-stage liver disease scores.
