The Hepatoprotective Effect of Sodium Nitrite on Cold Ischemia-Reperfusion Injury

Figure 4

Liver pathology scores decreased with nitrite. Increased hepatocyte swelling, increased cytoplasmic vacuolization, nuclear pyknosis, sinusoidal dilatation, and focal necrosis in LR only group with maximal injury at 18 hrs are observed. These findings were significantly reduced at 18 hrs with 25 μM of anion nitrite (2.4±0.8 versus 1.7±0.7). Data are expressed as mean ± SE. ^#𝑃<0.05 for corresponding measurements.